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Indus River, great trans-Himalayan river of South Asia. It is one of the longest rivers in the world, with a length of some 2,000 miles (3,200 km). Its total drainage area is about 450,000 square miles (1,165,000 square km), of which 175,000 square miles (453,000 square km) lie in the ranges and foothills of the Himalayas, the Hindu Kush, and the Karakoram Range; the rest is in the semiarid plains of Pakistan. The river’s annual...