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Transorbital lobotomy is a surgical procedure where nerve pathways in the brain's frontal lobe are severed from other areas. This was historically used to treat severe mental illnesses like schizophrenia and bipolar disorder.123

The procedure involved drilling holes in the skull or, in the case of transorbital lobotomy, forcing a picklike instrument through the eye socket to sever these connections. While some patients experienced reduced agitation, many suffered from apathy, lack of concentration, and diminished emotional response. The practice declined with the advent of more effective medications.1

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