Clozapine
pharmacology
Clozapine, antipsychotic drug primarily used in the treatment of severe schizophrenia, especially in instances when other treatments fail to improve symptoms. Clozapine is also particularly useful for reducing the risk of suicide in individuals with schizophrenia or schizoaffective disorder who have made repeated suicide attempts. It may also be used to treat certain other psychotic conditions, such as psychosis arising in Parkinson disease. Clozapine is considered a second-generation atypical antipsychotic drug. Unlike older first-generation “typical”...