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cisternal maturation model

biology

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The cisternal maturation model describes how proteins and lipids move through the Golgi apparatus. This model proposes that the Golgi is a dynamic organelle where new cisternae form at the cis face from fused vesicles. These cisternae then mature and move forward, eventually becoming trans cisternae. Vesicles are used primarily for retrograde transport back to the endoplasmic reticulum. This contrasts with the vesicular transport model, which suggests cisternae are stationary and vesicles move cargo between them. The Golgi apparatus, composed of stacked cisternae, modifies, sorts, and packages proteins and lipids for delivery to various destinations within or outside the cell.12

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