acute motor and sensory axonal neuropathy

Acute motor and sensory axonal neuropathy (AMSAN) is a subtype of Guillain-Barré syndrome, a rare autoimmune disorder affecting the peripheral nervous system. In AMSAN, the immune system mistakenly attacks the axon of peripheral nerves, which are responsible for transmitting signals for movement and sensation. This damage can lead to muscle weakness, numbness, and paralysis, affecting both motor and sensory functions. Symptoms can develop rapidly, often following a bacterial or viral infection. Treatment focuses on immunotherapy to reduce the immune system's attack on the nerves. Recovery varies, with some individuals experiencing full nerve regeneration while others may have long-lasting deficits.1