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Despite extensive investigation, the manner in which the COVID-19 pandemic started is yet undetermined. The leading hypothesis centers on the idea that SARS-CoV-2, the causative virus, originated in animals then emerged humans following an event related to zoonotic spillover. Pathogens that exist in animals sometimes develop the ability to infect humans, typically through genetic changes. This process, known as zoonotic spillover, can occur when humans come into direct contact with wildlife or domestic animals or...