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Friedel-Crafts acylation
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Friedel-Crafts acylation

chemistry
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Quick Summary

The Friedel-Crafts acylation is a synthetic reaction in organic chemistry used to synthesize ketones. This reaction involves the acylation of an aromatic hydrocarbon with an acyl chloride or acid anhydride, typically using anhydrous aluminum chloride as a catalyst. Acyl chlorides are highly reactive derivatives of carboxylic acids and readily react with aromatic rings in the presence of aluminum chloride to form ketones. This process is a specific type of the broader Friedel-Crafts reaction, named after chemists Charles Friedel and James Crafts.12

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2 Britannica Sources
  1. Friedel-Crafts reaction
  2. carboxylic acid - Reactions

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