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APC
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APC

gene
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The APC gene, or Adenomatous Polyposis Coli gene, is a tumor suppressor gene. Tumor suppressor genes normally regulate cell growth and inhibit proliferation. When mutated, they can contribute to the development of cancer.

An inherited mutation in the APC gene is linked to familial adenomatous polyposis, a condition characterized by the formation of numerous polyps in the colon, some of which can become cancerous. Unlike proto-oncogenes, both copies of a tumor suppressor gene must be altered to inactivate its function.123

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4 Britannica Sources
  1. tumor suppressor gene
  2. cancer - Other tumor suppressor genes
  3. APC
  4. tumor suppressor gene: Top Questions

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