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Nonnutritive sweeteners are substances that provide a sweet taste without significant caloric value. They are primarily used in low-calorie products like baked goods, soft drinks, and tabletop sweeteners. They are also beneficial for individuals managing diabetes and can help reduce the risk of tooth decay, as they are not metabolized by oral bacteria.12

While generally considered safe after rigorous toxicological testing, some nonnutritive sweeteners have faced scrutiny. High concentrations of saccharin and cyclamates in animal studies showed a link to bladder tumors, leading to bans or warnings in some regions. However, no direct evidence of human bladder cancer from consuming these sweeteners has been reported. Aspartame and acesulfame K are considered relatively safe with no evidence of carcinogenicity in animal studies.1

Unlike nutritive sweeteners, nonnutritive options do not add viscosity or texture, often requiring bulking agents in manufacturing.1

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2 Britannica Sources
  1. food additive
  2. sweetener

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