In Novum Testamentum ex diversorum utriusque linguae codicum collatione adnotationes

Lorenzo Valla's In Novum Testamentum ex diversorum utriusque linguae codicum collatione adnotationes (Annotations on the New Testament Collected from Various Codices in Each Language) was a significant work in humanist philology. Encouraged by scholars like Bessarion and Nicholas of Cusa, Valla applied critical methods to the New Testament text. This approach, which involved comparing various manuscripts in both Greek and Latin, aimed to establish a more accurate version of the text.

Valla's work was controversial, as it challenged traditional interpretations and the authority of St. Jerome, the translator of the Latin Vulgate Bible. The Adnotationes were later placed on the Roman Catholic Church's list of condemned books during the Counter-Reformation. Despite the controversy, Valla's application of humanist textual criticism to sacred texts was a pioneering effort.12