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For most people, a kiss is a familiar gesture of affection, greeting, or intimacy. But, because kissing often involves close contact and the exchange of saliva, it can also provide a route for certain infectious diseases to spread from one person to another. The risk varies widely depending on the disease, the mode of transmission, and individual circumstances, and many infections associated with kissing are also spread through other forms of close contact. The 12 diseases (or the pathogens responsible for the diseases) listed below are among those that can be transmitted during lip-to-lip contact, particularly through the associated saliva exchange during deep kissing.

Risk of Contracting STDs from Kissing

Sexually transmitted diseases (STDs), such as syphilis and AIDS, are rarely contracted from kissing an infected person. Human immunodeficiency virus (HIV) occurs infrequently in infected persons’ saliva. The syphilis-causing bacterium, on the other hand, can be transferred through kissing only via direct contact with active syphilis sores (chancres) in the mouth. The jury is still out on whether human papillomavirus (HPV) spreads through deep kissing.