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cardenolide

chemistry
Also known as: cardanolide

Quick Summary

Cardenolides are a group of organic compounds found in plants, such as milkweeds. These compounds possess a characteristic ring structure and can have a significant effect on the vertebrate heart, similar to the action of digitalis. They are often found in plants as glycosides, meaning they are linked to sugar residues.12

While the aglycone (the steroid part without the sugars) is less active, the glycosides themselves can be toxic and cause vomiting. Notable examples of cardiac glycosides include digitoxin, gitoxin, and digoxin, which are derived from the foxglove plant. These compounds have medicinal uses, particularly in treating heart conditions.21

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