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The white pulp of the spleen is a type of lymphoid tissue that typically surrounds the spleen's blood vessels. It contains plasma cells, lymphocytes, and lymphatic nodules, also known as follicles. Within the white pulp, germinal centers are sites where lymphocytes are produced. Similar to lymph nodes, the spleen's white pulp responds to antigens in the bloodstream by releasing macrophages, which are phagocytic cells that remove foreign material and initiate immune responses, including antibody production.12

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  1. spleen
  2. macrophage
  3. blood - Lymphocytes

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