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Coumadin; warfarin
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Coumadin; warfarin
Coumadin; warfarin The anticoagulant drug warfarin, marketed as Coumadin, typically is used to reduce the chances of heart attack or stroke caused by blood clots in the arteries and veins.

warfarin

drug
Also known as: Coumadin
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ā€¢History

warfarin, anticoagulant drug, marketed as Coumadin. Originally developed to treat thromboembolism (see thrombosis), it interferes with the liverā€™s metabolism of vitamin K, leading to production of defective coagulation factors. Warfarin therapy risks uncontrollable hemorrhage, either spontaneously or from any cut or bruise; it requires frequent checks to maintain the proper level in the blood. In high concentrations, warfarin is used as a rodent poison, causing death by internal bleeding.

This article was most recently revised and updated by Kara Rogers.