vincristine
Quick Summary
Vincristine is an alkaloid derived from the periwinkle plant. It is used, typically as its sulfate form, to treat certain human neoplastic diseases, such as acute leukemia. Vincristine is classified as an anticancer drug and works by stopping cell division during DNA replication and cell division by affecting spindle formation. It is one of the vinca alkaloids, which are plant-derived agents used in cancer treatment.123
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angiospermSignificance to humanssuch as acute leukemia (vincristine from the Madagascar periwinkle, Catharanthus roseus; Apocynaceae), and of heart problems (digitalis from foxglove, Digitalis purpurea; Plantaginaceae). Muscle relaxants derived from curare (
Read Moresuch as acute leukemia (vincristine from the Madagascar periwinkle, Catharanthus roseus; Apocynaceae), and of heart problems (digitalis from foxglove, Digitalis purpurea; Plantaginaceae). Muscle relaxants derived from curare (
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drugAnticancer drugsVinblastine and vincristine (vinca alkaloids), derived from the periwinkle plant, along with etoposide, act primarily to stop spindle formation within the dividing cell during DNA replication and cell division. These drugs are important agents in the treatment of leukemias, lymphomas, and testicular cancer. Etoposide, a semisynthetic derivative…
Read MoreVinblastine and vincristine (vinca alkaloids), derived from the periwinkle plant, along with etoposide, act primarily to stop spindle formation within the dividing cell during DNA replication and cell division. These drugs are important agents in the treatment of leukemias, lymphomas, and testicular cancer. Etoposide, a semisynthetic derivative…
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