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very-low-density lipoprotein
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Diagram showing how fatty acids are mobilized from adipose tissue, transported in the bloodstream, processed in the liver, and delivered as energy sources such as fatty acids, triglycerides, and ketones to the muscle, brain, and heart. Arrows illustrate the movement and conversion of lipids, glucose, glycerol, and ketones between adipocytes, liver, muscle, heart, and brain. Detailed diagram showing the transport of lipoproteins in the human body, illustrating how dietary fats and cholesterol are absorbed in the small intestine, packaged into chylomicrons, and transported through lymphatic vessels and the bloodstream. The diagram traces the conversion of chylomicrons to VLDL, IDL, LDL, and HDL particles, highlighting their roles in fat and cholesterol delivery, storage, and recycling, with labeled pathways to the liver, muscle, and adipose tissue, and includes cellu
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very-low-density lipoprotein

physiology
Also known as: VLDL
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Diagram showing how fatty acids are mobilized from adipose tissue, transported in the bloodstream, processed in the liver, and delivered as energy sources such as fatty acids, triglycerides, and ketones to the muscle, brain, and heart. Arrows illustrate the movement and conversion of lipids, glucose, glycerol, and ketones between adipocytes, liver, muscle, heart, and brain.
hormone signaling; adipose tissue When hormones signal the need for energy, fatty acids and glycerol are released from triglycerides stored in fat cells (adipocytes) and are delivered to organs and tissues in the body.

Very-low-density lipoprotein (VLDL) is a plasma lipoprotein primarily produced by the liver, with smaller contributions from the intestine. Lipoproteins are complex structures of lipids and proteins that transport fats throughout the body via the circulatory system. VLDL's main role is to deliver triglycerides, cholesterol, and fat-soluble vitamins to peripheral tissues.123

VLDL is characterized by a relatively high triglyceride content compared to its protein content. It is one of the major classes of circulating lipoproteins, alongside chylomicrons, intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). When VLDL releases its triglycerides in tissues, it forms an intermediate-density lipoprotein (IDL) remnant that returns to the liver. High concentrations of lipoproteins can lead to their deposition on artery walls, contributing to atherosclerosis.1342

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5 Britannica Sources
  1. VLDL
  2. very-low-density lipoprotein
  3. metabolic disease - Lipoprotein disorders
  4. lipid - Functions, origins, and recycling of apolipoproteins
  5. lipid - Very low-density lipoproteins (VLDL)

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