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The ureteric bud is a crucial component in the development of the permanent kidney, known as the metanephros, in reptiles, birds, and mammals. This bud originates as a dorsal outgrowth of the mesonephric duct and grows towards the mesenchyme, eventually forming the ureter. As it branches within the mesenchyme, it gives rise to the collecting tubules of the kidney. The mesenchyme, influenced by the ureteric bud's branches, then aggregates to form the excretory tubules. The development of these excretory tubules is dependent on the ureteric bud; if it fails to develop or reach the mesenchyme, no kidney will form.12

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