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Type I pneumocytes are thin, flat cells that line the walls of the pulmonary alveoli in the lungs. They cover 92-95% of the gas-exchange surface and, along with endothelial cells, form the air-blood barrier essential for diffusion. This barrier allows oxygen to enter the blood and carbon dioxide to leave it. These cells are crucial for efficient gas exchange due to their thinness and the large surface area of the alveoli.123

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