transmissible spongiform encephalopathy
Quick Summary
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases affecting animals, including humans. They are caused by prions, which are abnormal forms of normally harmless brain proteins. These prions accumulate in nerve cells, damaging them and leading to a spongy, pitted pattern in brain tissue.
Diseases in this category include bovine spongiform encephalopathy (BSE) in cattle, commonly known as mad cow disease, and Creutzfeldt-Jakob disease in humans. BSE, first identified in the United Kingdom in 1986, is thought to have originated from cattle consuming contaminated feed. This led to widespread concerns about a potential link to a new variant of Creutzfeldt-Jakob disease in humans. Measures such as feed bans were implemented to prevent further spread.12
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