topical immunomodulator

medication

Also known as: TIM

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Last updated

July 19, 2026

Quick Summary

Topical immunomodulators (TIMs) are steroid-free medications applied to the skin to treat dermatitis. They work by inhibiting the activation of immune substances. While they can help reduce symptoms and inflammation, TIMs are considered second-line treatments due to potentially serious side effects, such as an increased risk of lymphoma.1

Other treatments for dermatitis include topical corticosteroids, antihistamines, phototherapy, and photochemotherapy. Immunosuppressants, a broader class of drugs, are used to prevent organ transplant rejection and treat autoimmune diseases by inhibiting the immune system.12

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dermatitis
Environmental influences and treatment
Topical immunomodulators (TIMs), which are steroid-free skin medications, have been developed. These agents work by inhibiting the activation of immune substances. However, due to their potentially dangerous side effects (e.g., lymphoma), TIMs are considered second-line treatments for dermatitis. Other therapies used for dermatitis include antihistamines,…
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Topical immunomodulators (TIMs), which are steroid-free skin medications, have been developed. These agents work by inhibiting the activation of immune substances. However, due to their potentially dangerous side effects (e.g., lymphoma), TIMs are considered second-line treatments for dermatitis. Other therapies used for dermatitis include antihistamines,…
Read More