tissue typing
Quick Summary
Tissue typing, also known as histocompatibility testing, is a medical process used to determine how closely a donor's tissues match a recipient's. This is crucial for successful transplant surgery. The body's immune system can attack transplanted organs or tissues if they are recognized as foreign.
The primary factors involved are human leukocyte antigens (HLA), which are proteins found on the surface of most cells. These antigens are inherited and vary greatly among individuals. Tissue typing involves analyzing a person's HLA antigens to find a compatible match. Red blood cell antigens, like those in the ABO system, are also considered, as they can also cause rejection. A close match between donor and recipient minimizes the risk of the immune system rejecting the transplant.
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- human leukocyte antigen
…system is useful in tissue typing, in which tissues from one individual are analyzed to determine whether they can be successfully transplanted to another individual. A number of HLA genes are associated with human diseases, including certain autoimmune disorders and cancer.
Read More…system is useful in tissue typing, in which tissues from one individual are analyzed to determine whether they can be successfully transplanted to another individual. A number of HLA genes are associated with human diseases, including certain autoimmune disorders and cancer.
Read More 
major histocompatibility complex…which are collectively called a tissue type. The MHC also contains a variety of genes that code for other proteins—such as complement proteins, cytokines (chemical messengers), and enzymes—that are called class III MHC molecules.
Read More…which are collectively called a tissue type. The MHC also contains a variety of genes that code for other proteins—such as complement proteins, cytokines (chemical messengers), and enzymes—that are called class III MHC molecules.
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