thiamin pyrophosphate

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Diagram showing how B-vitamin coenzymes, such as vitamin B6, folic acid, and biotin, assist in metabolic pathways involving carbohydrates, fats, and proteins, highlighting their roles in energy production and the tricarboxylic acid cycle.

thiamin pyrophosphate

chemical compound

Also known as: TPP, thiamine pyrophosphate

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metabolism
The oxidation of pyruvate
…pyruvic acid decarboxylase (enzyme 1), thiamine pyrophosphate (TPP); in addition to carbon dioxide a hydroxyethyl–TPP–enzyme complex (“active acetaldehyde”) is formed [34]. Thiamine is vitamin B₁; the biological role of TPP was first revealed by the inability of vitamin B₁-deficient animals to oxidize pyruvate.
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…pyruvic acid decarboxylase (enzyme 1), thiamine pyrophosphate (TPP); in addition to carbon dioxide a hydroxyethyl–TPP–enzyme complex (“active acetaldehyde”) is formed [34]. Thiamine is vitamin B₁; the biological role of TPP was first revealed by the inability of vitamin B₁-deficient animals to oxidize pyruvate.
Read More