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tetramethylsilane

chemical compound
Also known as: TMS

Quick Summary

Tetramethylsilane, with the chemical formula Si(CH3)4, is a derivative of silane where all hydrogen atoms have been replaced by methyl groups. Silanes are compounds containing only silicon and hydrogen, with the general formula SinH2n + 2.1

Tetramethylsilane is notable for its use as a reference compound in proton magnetic resonance spectroscopy. In this technique, the absorption of all 12 of its hydrogen atoms is assigned a positional value of zero, serving as a standard against which other hydrogen atoms in a molecule are measured. This compound is an inert liquid added to samples for analysis.2

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