tetanus toxoid
Quick Summary
Tetanus is an acute infectious disease caused by toxins produced by the bacterium Clostridium tetani. These toxins attack the nervous system, leading to muscle rigidity and spasms, most notably in the jaw, earning it the nickname "lockjaw." Spores of Clostridium tetani are found in soil and can enter the body through any wound, especially deep ones that create an oxygen-free environment for the bacteria to grow.1
Vaccination with tetanus toxoid is highly effective in preventing the disease. Tetanus toxoid is a modified toxin that stimulates the body to produce antibodies. Widespread use of tetanus toxoid, particularly during World War II, dramatically reduced the incidence of tetanus. Routine immunization schedules, including booster doses, are crucial for maintaining immunity throughout life.2
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tetanusActive immunization with tetanus toxoid (prepared by chemical modification of toxin) is a relatively slow process, requiring weeks or months to become effective, and must be renewed every few years (booster doses). A first dose should be given to every accident victim, followed by two more doses several…
Read MoreActive immunization with tetanus toxoid (prepared by chemical modification of toxin) is a relatively slow process, requiring weeks or months to become effective, and must be renewed every few years (booster doses). A first dose should be given to every accident victim, followed by two more doses several…
Read More
infectious diseaseTetanus toxoidThe efficacy of active immunization against tetanus was illustrated most dramatically during World War II, when the introduction of tetanus toxoid among military personnel virtually eliminated the occurrence of the disease as a result of war-related injuries. Since then, the routine immunization of…
Read MoreThe efficacy of active immunization against tetanus was illustrated most dramatically during World War II, when the introduction of tetanus toxoid among military personnel virtually eliminated the occurrence of the disease as a result of war-related injuries. Since then, the routine immunization of…
Read More