sulfonylurea
Quick Summary
Sulfonylureas are a class of hypoglycemic compounds related to sulfonamides. They are used in the oral treatment of diabetes. These drugs work by stimulating the insulin-secreting beta cells of the pancreas to produce more insulin. While this effect may diminish with long-term use, plasma glucose levels generally remain low. The most serious, though rare, adverse effect of sulfonylureas is profound hypoglycemia, which can lead to coma in severe cases.12
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diabetes mellitusDrugs used to control blood glucose levelsSulfonylureas, such as glipizide and glimepiride, are considered hypoglycemic agents because they stimulate the release of insulin from beta cells in the pancreas, thus reducing blood glucose levels. The most common side effect associated with sulfonylureas is hypoglycemia (abnormally low blood glucose levels), which occurs…
Read MoreSulfonylureas, such as glipizide and glimepiride, are considered hypoglycemic agents because they stimulate the release of insulin from beta cells in the pancreas, thus reducing blood glucose levels. The most common side effect associated with sulfonylureas is hypoglycemia (abnormally low blood glucose levels), which occurs…
Read More- antidiabetic drugOral antidiabetic drugs
The sulfonylureas, for example, stimulate the insulin-secreting beta cells of the pancreas to produce more insulin. With long-term use, this effect appears to diminish, but plasma glucose levels remain low. The most serious adverse effect of these drugs, which occurs only rarely, is profound hypoglycemia; in…
Read MoreThe sulfonylureas, for example, stimulate the insulin-secreting beta cells of the pancreas to produce more insulin. With long-term use, this effect appears to diminish, but plasma glucose levels remain low. The most serious adverse effect of these drugs, which occurs only rarely, is profound hypoglycemia; in…
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