subthalamic nucleus
Quick Summary
The subthalamic nucleus is a small, paired nucleus located in the brain, specifically within the basal ganglia system. It plays a crucial role in motor control by influencing the timing and amount of activity that leaves the cerebral cortex.12
The subthalamic nucleus receives input from the cortex and thalamus and, in turn, influences the outflow from the striatum to the thalamus. It is part of a complex loop that helps refine motor signals, amplifying desired movements and suppressing unwanted ones. Dysfunction in this area can lead to movement disorders, such as those seen in Parkinson disease.21
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