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Substance P is a neuropeptide composed of 11 amino acids. It is found in the nervous system and the gastrointestinal tract.1

In the body, substance P plays a role in various functions:
* It causes the contraction of smooth muscle and dilation of blood vessels.1
* It acts as a potent neurotransmitter, particularly in transmitting signals from pain receptors.1
* It stimulates saliva production and inflammatory responses.2

While present in significant amounts in certain nerves and the digestive system, its exact role, especially in the gastrointestinal tract, is still being researched, with some uncertainty about whether it serves a primary function or is an evolutionary remnant.2

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