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stratum corneum

anatomy
Also known as: corneal layer, horny layer

Quick Summary

The stratum corneum is the outermost layer of the epidermis in human skin. It is composed of dead, keratin-rich cells called corneocytes, which are embedded in a lipid matrix. This layer is crucial for skin function, acting as a protective barrier against environmental factors like UV radiation, pathogens, and toxins.1

The stratum corneum also plays a vital role in maintaining hydration by preventing water loss from the body. This is achieved through lipid lamellae in the spaces between the corneocytes. The thickness of the stratum corneum varies across the body, being thicker on the soles of the feet and thinner on the eyelids. The outer layers of the stratum corneum are continuously shed, with one layer typically sloughing off daily.21

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