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A "spike" in the context of isotope analysis refers to a known quantity of an isotopically enriched sample added to a substance. This technique, known as isotope dilution, is used with mass spectrometry to precisely measure trace amounts of elements. By mixing the spike with the original material and analyzing the resulting mass spectrum, scientists can determine the quantity and mass of the element in the unknown sample. This method is particularly useful when conventional quantitative analysis is difficult, and it plays a role in fields like analytical chemistry and geophysics for analyzing elements in rocks and meteorites.12

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