sitagliptin

drug

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Last updated

July 20, 2026

Quick Summary

Sitagliptin is an antidiabetic drug used to manage type 2 diabetes mellitus. It works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This inhibition increases the levels of naturally produced incretins, which are gastrointestinal hormones that stimulate insulin release from the pancreas and help regulate blood glucose levels. Sitagliptin is taken orally and is often used in conjunction with other diabetes medications or lifestyle changes. While generally well-tolerated, potential side effects can occur.12

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antidiabetic drug
Other agents
A drug called sitagliptin specifically inhibits DPP-4, thereby increasing levels of naturally produced incretins. Semaglutide mimics the actions of glucagon-like peptide-1 (GLP-1), a hormone released in response to eating that causes delays in gastric emptying and induces a feeling of fullness. GLP-1 increases insulin production, helping regulate glucose…
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A drug called sitagliptin specifically inhibits DPP-4, thereby increasing levels of naturally produced incretins. Semaglutide mimics the actions of glucagon-like peptide-1 (GLP-1), a hormone released in response to eating that causes delays in gastric emptying and induces a feeling of fullness. GLP-1 increases insulin production, helping regulate glucose…
Read More