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The sinus venosus is an enlarged pouch that connects to the heart, formed by the merging of large veins. It serves as the pathway for venous blood to enter the heart in lower vertebrates and in the embryos of higher forms.1

In human anatomy, a venous sinus refers to channels within the dura mater, the brain's outer covering, that collect deoxygenated blood. Unlike veins, these sinuses lack muscular walls and are lined with endothelium. They receive blood from the brain's veins and connect to the internal jugular vein, eventually leading to the heart's upper right chamber.2

During embryonic development, the sinus venosus is an early component of the forming heart. It initially lies above the ventricle and bulbus cordis, and over time, it becomes incorporated into the right atrium of the heart.3

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