serum globulin

biochemistry

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July 15, 2026

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Serum globulins are a group of proteins found in blood serum that contain most of the blood's antibodies. These proteins are crucial for the immune system, as they help the body fight off infections.12

In human blood serum, about one-third of the protein content is in the globulin fraction, which is further divided into alpha-, beta-, and gamma-globulins. Gamma globulins, also known as immunoglobulins, are particularly important because they are the primary carriers of antibodies. When the body encounters foreign substances, it produces antibodies, which are a type of gamma globulin, to neutralize them.324

A deficiency in gamma globulins can lead to frequent infections due to an impaired ability to develop immunity. Amyloidosis is a condition where a filamentous protein derived from immunoglobulins accumulates in connective tissue.24

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…blood plasma) and increases in serum globulin (a specific group of proteins found in blood plasma and including immunoglobulins). Although other tests may also be abnormal in patients with acute liver disease, serum albumin levels are usually not reduced in the acute stage of the disease because that protein is…
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…blood plasma) and increases in serum globulin (a specific group of proteins found in blood plasma and including immunoglobulins). Although other tests may also be abnormal in patients with acute liver disease, serum albumin levels are usually not reduced in the acute stage of the disease because that protein is…
Read More