secondary hyperaldosteronism

Secondary hyperaldosteronism is a condition where the adrenal glands produce too much aldosterone due to an underlying issue. Aldosterone's main role is to help the kidneys retain salt and water, and excrete potassium.1

This condition arises from the body's natural mechanisms to compensate for salt and water loss, decreased blood volume, or reduced blood flow to the kidneys. Causes can include severe diarrhea, persistent vomiting, excessive perspiration, heart failure, cirrhosis of the liver, or a narrowed renal artery.1

Unlike primary hyperaldosteronism, secondary hyperaldosteronism typically does not cause high blood pressure or low serum potassium levels, except in cases involving renal artery disease. Treatment focuses on addressing the root cause, aiming to normalize hormone production. Medications that block aldosterone's effects, like spironolactone, may also be used.12