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Sebum is a fatty substance secreted by sebaceous glands, which are small oil-producing glands in the skin of mammals. These glands are typically attached to hair follicles and release sebum into the follicular duct, which then reaches the skin's surface. Sebum is a complex mixture of lipids, including triglycerides and wax esters, and it helps keep the skin flexible and prevents excessive water loss.12

Sebaceous glands are found all over the body except for the palms of the hands and soles of the feet, being most abundant on the scalp and face. Their activity is influenced by hormones, particularly androgens, and they become active around puberty. Sebum plays a role in the development of acne vulgaris, a common skin condition where the gland's outlet becomes blocked, leading to inflammation.123

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