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The sclera is the dense, fibrous, opaque white outer coat that encloses the eyeball, except for the transparent part known as the cornea. It is essentially a continuation of the cornea, with collagen fibers from the cornea seamlessly extending into the sclera. The sclera's structure, with its irregularly sized and arranged collagen fibrils, contributes to its opacity, unlike the cornea's uniform and parallel arrangement which allows for transparency.12

Inflammation of the sclera is called scleritis, which is a more severe and often painful condition than episcleritis, a milder inflammation of the superficial layers just above the sclera. Scleritis can be associated with underlying systemic disorders like tuberculosis or rheumatoid arthritis, though its cause is frequently unknown. In severe cases, scleritis can threaten the eye's health and visual function.34

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