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schizencephaly
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schizencephaly

birth defect
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Quick Summary

Schizencephaly is a rare birth defect characterized by the presence of slits or clefts in the cerebral hemispheres of the brain. This condition is a type of porencephaly.1

The exact cause is not fully understood, but it is believed to be related to improper neuronal migration during early fetal development. Genetic abnormalities and maternal factors, such as exposure to certain medications or toxins during pregnancy, may also play a role.1

The severity of schizencephaly can vary. When the slits affect both sides of the brain (bilateral), individuals typically experience developmental delays. If only one side of the brain is affected (unilateral), individuals may have one-sided weakness but potentially normal intelligence.1

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2 Britannica Sources
  1. cephalic disorder
  2. nervous system disease - Cephalic disorders

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