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Retinoids are synthetic or naturally occurring analogs of vitamin A. Retinoic acid, a specific type of retinoid, is derived from vitamin A and exists in two isomeric forms: tretinoin and isotretinoin. These compounds are used in the treatment of acne. The term "retinoid" was first used in 1976, while "retinoic acid" was first documented in 1960.12

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