renal tubule
Quick Summary
The renal tubule is a crucial component of the nephron, the functional unit of the kidney. Each kidney contains about a million nephrons, each with a long tubule. These tubules begin as a cuplike structure called the renal corpuscular capsule, which encloses the glomerulus, a cluster of capillaries.
The tubule then extends into the proximal convoluted tubule, followed by the loop of Henle, and then the distal convoluted tubule. Finally, the distal tubule leads to a collecting tubule, which transports urine to the renal pelvis.
The primary functions of the renal tubule are to reabsorb essential substances like water and salts back into the bloodstream and to excrete waste products in the form of urine. The specific sections of the tubule have specialized roles in concentrating urine and regulating the body's water and electrolyte balance.123
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renal systemTubule functionThe role of the tubules may be assessed by comparing the amounts of various substances in the filtrate and in the urine (Table 2).
Read MoreThe role of the tubules may be assessed by comparing the amounts of various substances in the filtrate and in the urine (Table 2).
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renal systemTubular secretionThe only difference between secretory and reabsorptive tubular mechanisms lies in the direction of transport; secretory mechanisms involve the addition of substances to the filtrate from the plasma in the peritubular capillaries. The small amount of secretion that does occur, except for the…
Read MoreThe only difference between secretory and reabsorptive tubular mechanisms lies in the direction of transport; secretory mechanisms involve the addition of substances to the filtrate from the plasma in the peritubular capillaries. The small amount of secretion that does occur, except for the…
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bone diseaseMetabolic bone disease…units of the kidney, the tubules and the glomerulus, are associated with two groups of bone diseases: the former with a low level of phosphate in the blood (hypophosphatemia) and the latter with renal osteodystrophy (see below), both characterized by rickets and osteomalacia. In addition, kidney transplantation is associated with…
Read More…units of the kidney, the tubules and the glomerulus, are associated with two groups of bone diseases: the former with a low level of phosphate in the blood (hypophosphatemia) and the latter with renal osteodystrophy (see below), both characterized by rickets and osteomalacia. In addition, kidney transplantation is associated with…
Read More- Hartnup disease
…the transport system in the kidney tubule that normally reabsorbs tryptophan into the body circulation is defective. As a result, the concentration of tryptophan increases in the urine and decreases in the blood, and there is less tryptophan available for the synthesis of niacin.
Read More…the transport system in the kidney tubule that normally reabsorbs tryptophan into the body circulation is defective. As a result, the concentration of tryptophan increases in the urine and decreases in the blood, and there is less tryptophan available for the synthesis of niacin.
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