renal amyloidosis
Quick Summary
Renal amyloidosis is a condition where abnormal protein deposits, called amyloid, accumulate in the kidneys, hindering their normal function. Amyloid is formed when proteins misfold into a fibrous structure. This can lead to kidney failure.12
There are different types of amyloidosis:
* Primary amyloidosis: Occurs without an underlying disease and is linked to abnormal antibody production.1
* Secondary amyloidosis: Develops in association with chronic diseases like rheumatoid arthritis or tuberculosis.1
* Hereditary amyloidosis: Caused by inherited genetic mutations, often affecting the nervous system but can also impact kidneys.1
Symptoms vary depending on the extent of kidney involvement and can include fatigue, thirst, and frequent urination. In advanced stages, it can lead to uremia, a buildup of waste products in the blood. Treatment focuses on managing symptoms and addressing underlying causes.21
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