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The red nucleus is a large, centrally located structure within the midbrain's tegmentum. It plays a role in coordinating sensorimotor information. This nucleus receives input from the cerebellum and the motor cortex.12

From the caudal part of the red nucleus, the rubrospinal tract originates. This tract's fibers cross over at midbrain levels and descend into the spinal cord. There, they influence interneurons that facilitate flexor muscle tone and reciprocally inhibit extensor muscle tone. The rubrospinal tract is thus influenced by both the motor cortex and the cerebellum.21

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