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reactive arthritis, disorder characterized primarily by joint pain that also sometimes affects the eyes, urogenital tract, and skin on the palms of the hands and soles of the feet. The cause of reactive arthritis is unclear, but symptoms typically are triggered by a sexually transmitted disease or a gastrointestinal infection. Presumably, reactive arthritis reflects an aberrant immune response to various infectious agents, such as Chlamydia, Campylobacter, Shigella, and other bacteria that occur in the genitals...