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A quintuplet refers to one of five offspring produced in the same pregnancy. Multiple births, including quintuplets, are exceptional in humans, with twins being the most common. Quintuplets can arise from a single fertilized egg (monozygotic) or multiple fertilized eggs (dizygotic). The Dionne quintuplets, born in 1934, were the first documented set to survive infancy and became international celebrities. Their survival was attributed to advanced medical care, and biological studies confirmed they originated from a single fertilized egg that underwent repeated splitting. Multiple births, especially higher-order multiples like quintuplets, are often premature and face greater health risks.123

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