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Protoplasmic astrocytes are a type of star-shaped cell, called neuroglia, found in the nervous system of both invertebrates and vertebrates. Unlike fibrous astrocytes, which are found in the white matter of the central nervous system, protoplasmic astrocytes are located in the gray matter. They have fewer fibrils in their cytoplasm and their organelles are sparse.1

Protoplasmic astrocytes play a role in the nervous system's response to injury by dividing and occupying spaces left by damaged neurons. They are also believed to absorb neurotransmitters like glutamate and GABA, which helps regulate communication between nerve cells at the synapses.12

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