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Proestrus is a phase in the reproductive cycle of female mammals, preceding estrus (heat). During proestrus, preparatory physiological changes occur, including the maturation of ovarian follicles under the influence of follicle-stimulating hormone. These follicles produce estrogen, which stimulates the thickening of the uterine lining (endometrium) in anticipation of potential fertilization. This period is crucial for preparing the female's body for mating and potential pregnancy.12

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