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principle of segregation

genetics
Also known as: Mendel’s first law, law of segregation

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The principle of segregation is one of Gregor Mendel's fundamental laws of heredity, formulated in 1865. It states that the two members (alleles) of a gene pair separate during the formation of sex cells (gametes) in a parent organism. This means that each gamete receives only one allele from each pair.12

When these gametes unite during fertilization, the offspring inherit one allele from each parent. This segregation ensures that traits are passed down as distinct units, rather than blending. For example, if a pea plant has alleles for both purple flowers (R) and white flowers (r), the law of segregation explains how these alleles separate into different gametes, leading to predictable ratios of traits in subsequent generations. This principle is crucial for understanding how genetic variation is maintained and passed on.321

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