plasmin

biology

Also known as: fibrinolysin

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Last updated

July 1, 2026

Quick Summary

Plasmin is a proteolytic enzyme found in the blood that plays a crucial role in dissolving blood clots. It is formed from its precursor, plasminogen, and is a key component of the body's fibrinolytic system, which is responsible for breaking down fibrin and fibrinogen. This process is essential for wound healing and preventing excessive clot formation.12

Fibrinolytic drugs, such as streptokinase, urokinase, and tissue plasminogen activator (t-PA), work by activating plasmin to dissolve clots. These agents are used therapeutically to treat conditions like deep vein thrombosis and heart attacks by restoring blood flow. However, excessive plasmin activity can lead to bleeding complications.23

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milk leg
…further clotting while the body’s plasmin (also called fibrinolysin) dissolves the blockage, and antibiotics are used to combat any infection. The leg is bandaged to prevent collection of fluid in the tissues (edema). Severe occlusion may require surgical treatment. If the clot detaches there is danger of pulmonary artery blockage.
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…further clotting while the body’s plasmin (also called fibrinolysin) dissolves the blockage, and antibiotics are used to combat any infection. The leg is bandaged to prevent collection of fluid in the tissues (edema). Severe occlusion may require surgical treatment. If the clot detaches there is danger of pulmonary artery blockage.
Read More