phosphatidylserine

chemical compound

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July 23, 2026

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Phosphatidylserine is a type of phospholipid, which are crucial fat-like substances found in living cells. Phospholipids have a unique structure with a water-attracting (hydrophilic) phosphate end and a water-repelling (hydrophobic) fatty acid end. This amphipathic nature allows them to form the lipid bilayer, the fundamental structure of all cell membranes.1

Serine, along with derivatives like ethanolamine, is a key component of phospholipids within biological membranes. Phosphatidylserine, also known as cephalin, is widespread in both plants and animals and plays a significant role in cellular structure and metabolism.21

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metabolism
Formation of lipids
…1-phosphate—to form CMP and, respectively, phosphatidylserine, phosphatidylinositol (in [85b]), or 3-phosphatidyl-glycerol 1′-phosphate (PGP; in [85c]). These reactions differ from those of polysaccharide biosynthesis ([79], [82]) in that phosphate is retained in the phospholipid, and the nucleotide product (CMP) is therefore a nucleoside monophosphate rather than the diphosphate. These compounds can…
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…1-phosphate—to form CMP and, respectively, phosphatidylserine, phosphatidylinositol (in [85b]), or 3-phosphatidyl-glycerol 1′-phosphate (PGP; in [85c]). These reactions differ from those of polysaccharide biosynthesis ([79], [82]) in that phosphate is retained in the phospholipid, and the nucleotide product (CMP) is therefore a nucleoside monophosphate rather than the diphosphate. These compounds can…
Read More