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The parietal pleura is a membrane that lines the thoracic cavity, which is the space within the chest that contains the lungs and heart. This membrane folds back at the root of the lung to become the visceral pleura, which covers the surface of the lungs. In a healthy state, these two pleural layers are in direct contact. The space between them, the pleural cavity, normally contains a small amount of lubricating fluid. Disorders of the pleura can include inflammation (pleurisy), fluid accumulation (pleural effusion), or tumors like mesothelioma.12

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