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Panhypopituitarism is a condition characterized by the deficiency of one or all hormones produced by the pituitary gland. This deficiency results from damage to the pituitary gland or the hypothalamus, which controls the pituitary. Causes can include tumors, infections, or postpartum hemorrhage (Sheehan syndrome).1

The pituitary gland, often called the "master gland," secretes hormones that regulate other endocrine glands and tissues. When all pituitary hormones are deficient, the condition is specifically known as panhypopituitarism. Symptoms can include adrenal insufficiency, hypothyroidism, and gonadal failure.21

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