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In statistics, a p-value represents the probability of obtaining observed results, or more extreme results, if the null hypothesis is true. The null hypothesis is a statement of no effect or no difference.123

A low p-value (typically less than 0.05) suggests that the observed data is unlikely to have occurred by random chance alone, leading to the rejection of the null hypothesis and the conclusion that the result is statistically significant. Conversely, a high p-value indicates that the observed results are likely due to random variation, and the null hypothesis cannot be rejected. Statistical significance does not imply the importance or practical impact of a finding, only that it is unlikely to be due to chance.23

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